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Kuan-Boone Tan Selected Research

safingol (sphinganine)

8/2014Liposomal codelivery of a synergistic combination of bioactive lipids in the treatment of acute myeloid leukemia.
6/2012In vivo efficacy of a novel liposomal formulation of safingol in the treatment of acute myeloid leukemia.
9/2011Role of reactive oxygen species in the synergistic cytotoxicity of safingol-based combination regimens with conventional chemotherapeutics.
12/2009The role of protein kinase C in the synergistic interaction of safingol and irinotecan in colon cancer cells.

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Kuan-Boone Tan Research Topics

Disease

4Neoplasms (Cancer)
12/2013 - 10/2009
2Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
08/2014 - 06/2012
1Hemolysis
06/2012
1Colonic Neoplasms (Colon Cancer)
12/2009
1Drug-Related Side Effects and Adverse Reactions
10/2009

Drug/Important Bio-Agent (IBA)

4safingol (sphinganine)IBA
08/2014 - 12/2009
3Drug CombinationsIBA
12/2013 - 12/2009
2LipidsIBA
08/2014 - 10/2009
2Irinotecan (Camptosar)FDA LinkGeneric
12/2013 - 12/2009
2Liposomes (Liposome)IBA
12/2013 - 10/2009
2SphingolipidsIBA
06/2012 - 09/2011
1CeramidesIBA
08/2014
1Doxorubicin (Adriamycin)FDA LinkGeneric
12/2013
1Reactive Oxygen Species (Oxygen Radicals)IBA
09/2011
1Fluorouracil (Carac)FDA LinkGeneric
12/2009
1Protein Kinase CIBA
12/2009
1Pharmaceutical PreparationsIBA
10/2009

Therapy/Procedure

2Therapeutics
09/2011 - 10/2009
1Induction Chemotherapy
06/2012
1Drug Therapy (Chemotherapy)
12/2009